ISG15 (NM_005101) Human Mass Spec Standard

Specifications

Product Data
Description	ISG15 MS Standard C13 and N15-labeled recombinant protein (NP_005092)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201235
Predicted MW	17.9 kDa
Protein Sequence	Sequence Link (showhide) >RC201235 protein sequence Red=Cloning site Green=Tags(s) MGWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSGVALQDRVPLASQGLGPGST VLLVVDKCDEPLNILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEY GLKPLSTVFMNLRLRGGGTEPGGRS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005092
RefSeq Size	685
RefSeq ORF	495
Synonyms	G1P2; hUCRP; IFI15; IMD38; IP17; UCRP
Locus ID	9636
Cytogenetics	1p36.33
Summary	The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	RIG-I-like receptor signaling pathway

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