UBE2G1 (NM_003342) Human Mass Spec Standard

Specifications

Product Data
Description	UBE2G1 MS Standard C13 and N15-labeled recombinant protein (NP_003333)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201159
Predicted MW	19.3 kDa
Protein Sequence	Sequence Link (showhide) >RC201159 representing NM_003342 Red=Cloning site Green=Tags(s) MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPP KMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVD AAKEWREDRNGEFKRKVARCVRKSQETAFE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003333
RefSeq Size	4208
RefSeq ORF	510
Synonyms	E217K; UBC7; UBE2G
Locus ID	7326
Cytogenetics	17p13.2
Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]
Protein Pathways	Parkinson's disease, Ubiquitin mediated proteolysis

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