SFXN3 (NM_030971) Human Mass Spec Standard

Specifications

Product Data
Description	SFXN3 MS Standard C13 and N15-labeled recombinant protein (NP_112233)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200974
Predicted MW	36 kDa
Protein Sequence	Sequence Link (showhide) >RC200974 protein sequence Red=Cloning site Green=Tags(s) MESKMGELPLDINIQEPRWDQSTFLGRARHFFTVTDPRNLLLSGAQLEASRNIVQNYRAGVVTPGITEDQ LWRAKYVYDSAFHPDTGEKVVLIGRMSAQVPMNMTITGCMLTFYRKTPTVVFWQWVNQSFNAIVNYSNRS GDTPITVRQLGTAYVSATTGAVATALGLKSLTKHLPPLVGRFVPFAAVAAANCINIPLMRQRELQVGIPV ADEAGQRLGYSVTAAKQGIFQVVISRICMAIPAMAIPPLIMDTLEKKDFLKRRPWLGAPLQVGLVGFCLV FATPLCCALFPQKSSIHISNLEPELRAQIHEQNPSVEVVYYNKGL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_112233
RefSeq Size	3129
RefSeq ORF	975
Synonyms	BA108L7.2; SFX3; SLC56A3
Locus ID	81855
Cytogenetics	10q24.31
Summary	Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778).[UniProtKB/Swiss-Prot Function]
Protein Families	Transmembrane

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