AKIRIN2 (NM_018064) Human Mass Spec Standard

Specifications

Product Data
Description	AKIRIN2 MS Standard C13 and N15-labeled recombinant protein (NP_060534)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200881
Predicted MW	22.5 kDa
Protein Sequence	Sequence Link (showhide) >RC200881 protein sequence Red=Cloning site Green=Tags(s) MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPTSAAASPLSAAAATAASFSAAAASPQKYLRMEPSPFG DVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFLLSGPASPGTSSAASSPLKKEQ PLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHDQIMRRYGEQPASYVS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_060534
RefSeq Size	1948
RefSeq ORF	609
Synonyms	C6orf166; dJ486L4.2; FBI1
Locus ID	55122
Cytogenetics	6q15
Summary	Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).[UniProtKB/Swiss-Prot Function]

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