Thyroid Hormone Receptor alpha (THRA) (NM_003250) Human Mass Spec Standard

CAT#: PH300735

THRA MS Standard C13 and N15-labeled recombinant protein (NP_003241)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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    • 100 ul

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Specifications

Product Data
Description THRA MS Standard C13 and N15-labeled recombinant protein (NP_003241)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200735
Predicted MW 54.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003241
RefSeq Size 2566
RefSeq ORF 1470
Synonyms AR7; c-ERBA-1; CHNG6; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA1; THRA2; TRalpha
Locus ID 7067
Cytogenetics 17q21.1
Summary The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Neuroactive ligand-receptor interaction
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