FKBP1B (NM_054033) Human Mass Spec Standard

Specifications

Product Data
Description	FKBP1B MS Standard C13 and N15-labeled recombinant protein (NP_473374)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200667
Predicted MW	8.8 kDa
Protein Sequence	Sequence Link (showhide) >RC200667 protein sequence Red=Cloning site Green=Tags(s) MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQLGPL SPLPICPHPC TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_473374
RefSeq Size	1016
RefSeq ORF	240
Synonyms	FKBP1L; FKBP12.6; OTK4; PKBP1L; PPIase
Locus ID	2281
Cytogenetics	2p23.3
Summary	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome

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