ROC1 (RBX1) (NM_014248) Human Mass Spec Standard

Specifications

Product Data
Description	RBX1 MS Standard C13 and N15-labeled recombinant protein (NP_055063)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200348
Predicted MW	12.3 kDa
Protein Sequence	Sequence Link (showhide) >RC200348 protein sequence Red=Cloning site Green=Tags(s) MAAAMDVDTPSGTNSGAGKKRFEVKKWNAVALWAWDIVVDNCAICRNHIMDLCIECQANQASATSEECTV AWGVCNHAFHFHCISRWLKTRQVCPLDNREWEFQKYGH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055063
RefSeq Size	906
RefSeq ORF	324
Synonyms	BA554C12.1; RNF75; ROC1
Locus ID	9978
Cytogenetics	22q13.2
Summary	This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5.[provided by RefSeq, Sep 2010]
Protein Families	Druggable Genome
Protein Pathways	Cell cycle, Nucleotide excision repair, Oocyte meiosis, Pathways in cancer, Renal cell carcinoma, TGF-beta signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway

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