NDE1 (NM_017668) Human Mass Spec Standard

CAT#: PH300179

NDE1 MS Standard C13 and N15-labeled recombinant protein (NP_060138)



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CNY 19520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description NDE1 MS Standard C13 and N15-labeled recombinant protein (NP_060138)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200179
Predicted MW 37.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_060138
RefSeq Size 3222
RefSeq ORF 1005
Synonyms HOM-TES-87; LIS4; MHAC; NDE; NUDE; NUDE1
Locus ID 54820
Cytogenetics 16p13.11
Summary This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
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