MADM (NRBP1) (NM_013392) Human Mass Spec Standard

Specifications

Product Data
Description	NRBP1 MS Standard C13 and N15-labeled recombinant protein (NP_037524)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200107
Predicted MW	59.8 kDa
Protein Sequence	Sequence Link (showhide) >RC200107 protein sequence Red=Cloning site Green=Tags(s) MSEGESQTVLSSGSDPKVESSSSAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREE VNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIK ENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFI QHNGLIKIGSVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGES SYVPQEAISSAIQLLEDPLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPE NALEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEV TSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNENIPELA AELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_037524
RefSeq Size	2212
RefSeq ORF	1605
Synonyms	BCON3; MADM; MUDPNP; NRBP
Locus ID	29959
Cytogenetics	2p23.3
Summary	May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Protein Kinase

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