HEK293T cell lysate - untransfected cell lysate (negative control)
CAT#: LY500001
HEK293T cell lysate - untransfected cell lysate (negative control)
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CNY 1,140.00
货期*
3周
规格
Cited in 381 publications. |
Product images

Specifications
Product Data | |
Tissue | Embryonic kidney cell line |
Host | Human |
Lysis Buffer | Modified RIPA buffer (25mM Tris-HCl pH7.6, 150mM NaCl, 1% NP-40, 1mM EDTA, 1xProteinase inhibitor cocktail mix (Sigma) and 1mM Na3VO4) |
Component | 1 vial of 100ug whole cell lysate in RIPA buffer 1 vial of 250ul 2xSDS Sample Buffer (4% SDS, 125mM Tris-HCl pH6.8, 10% Glycerol, 0.002% Bromophenol blue, 100mM DTT) |
Storage | Shipped on dry ice. Store the lysate at -80°C and avoid repeated freeze / thaw cycles. The lysate is stable for at least one year from date of shipping when stored at -80°C. After incubation with SDS-PAGE sample buffer, SDS-PAGE samples need to be stored in -20°C for long term storage. |
Citations (381)
The use of this Proteins has been cited in the following citations: |
---|
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes
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Molecular Neurodegeneration
,PubMed ID 35841044
|
Coordination of metal center biogenesis in human cytochrome c oxidase
,null,
Nature Communications
,PubMed ID 35750769
|
Ablation of Tmcc2 Gene Impairs Erythropoiesis in Mice
,null,
International Journal of Molecular Sciences
,PubMed ID 35563652
|
FL118, acting as a ‘molecular glue degrader’, binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy, et al. FL118, acting as a ‘molecular glue degrader’, binds to dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy
,null,
Clinical and Translational Medicine
,PubMed ID 35604033
|
Insufficiency of hepatocyte growth factor activator inhibitor‐1 confers lymphatic invasion of tongue carcinoma cells, et al. Insufficiency of hepatocyte growth factor activator inhibitor‐1 confers lymphatic invasion of tongue carcinoma cells
,null,
Cancer Science
,PubMed ID 35332604
|
An anti-influenza A virus microbial metabolite acts by degrading viral endonuclease PA
,null,
Nature Communications
,PubMed ID 35440123
|
SOX4 and RELA Function as Transcriptional Partners to Regulate the Expression of TNF- Responsive Genes in Fibroblast-Like Synoviocytes
,null,
Frontiers in Immunology
,PubMed ID 35529852
|
CD164 is a host factor for lymphocytic choriomeningitis virus entry
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 35235462
|
The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal, et al. The roles of HMGB1‐produced DNA gaps in DNA protection and aging biomarker reversal
,null,
FASEB BioAdvances
,PubMed ID 35664831
|
The cross-talk between PARylation and SUMOylation in C/EBPβ at K134 site participates in pathological cardiac hypertrophy
,null,
International Journal of Biological Sciences
,PubMed ID 35002525
|
RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation
,null,
Nature Communications
,PubMed ID 34887419
|
Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E, protects human neurons against oxidative/neuroexcitotoxic stress via β-arrestin/ERK signaling
,null,
Cellular and Molecular Life Sciences
,PubMed ID 34966948
|
Endoplasmic reticulum-translocation is essential for APOL1 cellular toxicity
,null,
iScience
,PubMed ID 35072009
|
Clinical and Laboratory Features in Anti-NF155 Autoimmune Nodopathy
,null,
Neurology® Neuroimmunology & Neuroinflammation
,PubMed ID 34728497
|
ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling
,null,
Journal of Cell Science
,PubMed ID 34557909
|
An ionic lock and a hydrophobic zipper mediate the coupling between an insect pheromone receptor BmOR3 and downstream effectors
,null,
The Journal of Biological Chemistry
,PubMed ID 34480896
|
MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer
,null,
Molecular Cancer
,PubMed ID 34521423
|
A cancer-unique glycan: de-N-acetyl polysialic acid (dPSA) linked to cell surface nucleolin depends on re-expression of the fetal polysialyltransferase ST8SIA2 gene
,null,
Journal of Experimental & Clinical Cancer Research : CR
,PubMed ID 34544457
|
Application Route and Immune Status of the Host Determine Safety and Oncolytic Activity of Oncolytic Coxsackievirus B3 Variant PD-H
,null,
Viruses
,PubMed ID 34696348
|
Local adenoviral delivery of soluble CD200R-Ig enhances antitumor immunity by inhibiting CD200-β-catenin-driven M2 macrophage
,null,
Molecular Therapy Oncolytics
,PubMed ID 34703882
|
Osteoblast-derived EGFL6 couples angiogenesis to osteogenesis during bone repair
,null,
Theranostics
,PubMed ID 34815781
|
A proteome-wide genetic investigation identifies several SARS-CoV-2-exploited host targets of clinical relevance
,null,
eLife
,PubMed ID 34402426
|
Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice
,null,
Nature Communications
,PubMed ID 34433814
|
Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism
,null,
Cell Death Discovery
,PubMed ID 34290233
|
Diverse mitochondrial abnormalities in a new cellular model of TAFFAZZIN deficiency are remediated by cardiolipin-interacting small molecules
,null,
The Journal of Biological Chemistry
,PubMed ID 34314685
|
Nucleotide‐binding domain and leucine‐rich‐repeat‐containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung‐like changes
,null,
Aging Cell
,PubMed ID 34087956
|
Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome
,null,
Journal of Medicinal Chemistry
,PubMed ID 34137257
|
YIV-906 potentiated anti-PD1 action against hepatocellular carcinoma by enhancing adaptive and innate immunity in the tumor microenvironment
,null,
Scientific Reports
,PubMed ID 34188068
|
The role of TNFRSF11B in development of osteoarthritic cartilage
,null,
Rheumatology (Oxford, England)
,PubMed ID 33989379
|
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue
,null,
Nature Communications
,PubMed ID 34016966
|
NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells
,null,
Cell Reports Medicine
,PubMed ID 34095881
|
Echinoderm Microtubule Associated Protein Like 1 Is Indispensable for Oocyte Spindle Assembly and Meiotic Progression in Mice
,null,
Frontiers in Cell and Developmental Biology
,PubMed ID 34124073
|
,null,
Drug Metabolism and Disposition
,PubMed ID 32114507
|
Inhibitory effects of α-Mangostin on T cell cytokine secretion via ORAI1 calcium channel and K+ channels inhibition
,null,
PeerJ
,PubMed ID 33717700
|
Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammation
,null,
Nature Communications
,PubMed ID 33568645
|
Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure
,null,
The Journal of Biological Chemistry
,PubMed ID 33127645
|
Correction of vasopressin deficit in the lateral septum ameliorates social deficits of mouse autism model
,null,
The Journal of Clinical Investigation
,PubMed ID 33232306
|
Identification of Key Phospholipids That Bind and Activate Atypical PKCs
,null,
Biomedicines
,PubMed ID 33419210
|
SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function
,null,
EMBO Molecular Medicine
,PubMed ID 33428810
|
Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer’s disease neuropathology
,null,
Molecular Neurodegeneration
,PubMed ID 33517893
|
Ese-3 contributes to colon cancer progression by downregulating EHD2 and transactivating INPP4B
,null,
American Journal of Cancer Research
,PubMed ID 33520362
|
Lysophospholipids Contribute to Oxaliplatin-Induced Acute Peripheral Pain
,null,
The Journal of Neuroscience
,PubMed ID 33158961
|
NMIHBA results from hypomorphic PRUNE1 variants that lack short-chain exopolyphosphatase activity
,null,
Human Molecular Genetics
,PubMed ID 33105479
|
Seizure-related 6 homolog like 2 autoimmunity
,null,
Neurology® Neuroimmunology & Neuroinflammation
,PubMed ID 33144342
|
A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome
,null,
The Journal of Experimental Medicine
,PubMed ID 32725126
|
The palmitoyl acyltransferases ZDHHC5 and ZDHHC8 are uniquely present in DRG axons and control retrograde signaling via the Gp130/JAK/STAT3 pathway
,null,
The Journal of Biological Chemistry
,PubMed ID 32958558
|
Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis
,null,
Scientific Reports
,PubMed ID 33033277
|
Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway
,null,
BMC Cancer
,PubMed ID 33069212
|
Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling
,null,
PLoS Genetics
,PubMed ID 33104735
|
VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons.
,null,
ACS chemical neuroscience
,PubMed ID 33143429
|
TRPV3 endogenously expressed in murine colonic epithelial cells is inhibited by the novel TRPV3 blocker 26E01.
,null,
Cell calcium
,PubMed ID 33161279
|
lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM1
,null,
Molecular Therapy Oncolytics
,PubMed ID 33313387
|
Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs
,null,
Genome Medicine
,PubMed ID 32988399
|
20-HETE Enzymes and Receptors in the Neurovascular Unit: Implications in Cerebrovascular Disease
,null,
Frontiers in Neurology
,PubMed ID 33013649
|
Interactions of Antibodies to the Gram-Negative Gastric Bacterium Helicobacter pylori with the Synaptic Calcium Sensor Synaptotagmin 5, Correlate to Impaired Vesicle Recycling in SiMa Human Neuroblastoma Cells
,Kleine, AD;Reuss, B;,
J. Mol. Neurosci. 2020
,PubMed ID 32860155
[Negative Control]
|
Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells
,null,
Cells
,PubMed ID 32756469
|
Localization of ZIP14 and ZIP8 in HIBCPP Cells
,null,
Brain Sciences
,PubMed ID 32784388
|
p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease
,null,
The Journal of Clinical Investigation
,PubMed ID 32804155
|
Novel monoclonal antibodies to the SERINC5 HIV-1 restriction factor detect endogenous and virion-associated SERINC5
,null,
mAbs
,PubMed ID 32835602
|
Unveiling the Physical and Functional Niches of FAM26F by Analyzing Its Subcellular Localization and Novel Interacting Partners
,null,
ACS Omega
,PubMed ID 32923759
|
G-quadruplexes offer a conserved structural motif for NONO recruitment to NEAT1 architectural lncRNA
,null,
Nucleic Acids Research
,PubMed ID 32496517
|
ERMAP is a B7 family-related molecule that negatively regulates T cell and macrophage responses.
,null,
Cellular molecular immunology
,PubMed ID 32620788
|
Ribosome collisions trigger cis-acting feedback inhibition of translation initiation
,null,
eLife
,PubMed ID 32657267
|
Clinical characteristics and outcome of patients with autoimmune encephalitis: clues for paraneoplastic aetiology.
,null,
European journal of neurology
,PubMed ID 32412135
|
Immunoadsorption and Plasma Exchange in Seropositive and Seronegative Immune-Mediated Neuropathies
,null,
Journal of Clinical Medicine
,PubMed ID 32605107
|
Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow
,null,
The Journal of Clinical Investigation
,PubMed ID 32182215
|
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination
,null,
Nature Communications
,PubMed ID 32366851
|
Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)
,null,
Frontiers in Cellular and Infection Microbiology
,PubMed ID 32547960
|
Serum glial fibrillary acidic protein (GFAP)-antibody in idiopathic intracranial hypertension.
,null,
The International journal of neuroscience
,PubMed ID 32303142
|
Distinct shear-induced Ca2+ signaling in the left and right atrial myocytes: Role of P2 receptor context.
,null,
Journal of molecular and cellular cardiology
,PubMed ID 32305361
|
Activated αIIbβ3 on platelets mediates flow-dependent NETosis via SLC44A2
,null,
eLife
,PubMed ID 32314961
|
A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury
,null,
Nature Communications
,PubMed ID 32317630
|
Glial fibrillary acidic protein (GFAP)-antibody in children with focal seizures of undetermined cause.
,null,
Acta neurologica Belgica
,PubMed ID 32333263
|
Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes
,null,
PLoS ONE
,PubMed ID 32353084
|
Clinical and genomic characteristics of LAMA2 related congenital muscular dystrophy in a patients' cohort from Qatar. A population specific founder variant.
,null,
Neuromuscular disorders : NMD
,PubMed ID 32444167
|
Genetically encoded protein sulfation in mammalian cells
,null,
Nature chemical biology
,PubMed ID 32198493
|
Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1
,null,
Journal of proteome research
,PubMed ID 31903766
|
Glucocorticoids regulate AKR1D1 activity in human liver invitro and in vivo
,null,
The Journal of Endocrinology
,PubMed ID 32106090
|
Red-kerneled rice proanthocyanidin inhibits arachidonate 5-lipoxygenase and decreases psoriasis-like skin inflammation.
,null,
Archives of biochemistry and biophysics
,PubMed ID 32112739
|
Deciphering anti-MOG IgG antibodies: Clinical and radiological spectrum, and comparison of antibody detection assays.
,null,
Journal of the neurological sciences
,PubMed ID 31954354
|
A systematic approach to quantitative Western blot analysis
,Pillai-Kastoori, L;Schutz-Geschwender, A;Harford, J;,
Analytical Biochemistry 2020
,PubMed ID 32007473
[Negative Control]
|
Transcriptomic profiling of cell-free and vesicular microRNAs from matched arterial and venous sera
,Hermann, S;Buschmann, D;Kirchner, B;Borrmann, M;Brandes, F;Kotschote, S;Bonin, M;Lindemann, A;Reithmair, M;Schelling, G;Pfaffl, M;,
Journal of Extracellular Vesicles 2019
,PubMed ID 31632620
[Negative Ccontrol]
|
Antibody Validation for Western blot: By the User, for the User
,Pillai-Kastoori, L;Heaton, S;Shiflett, SD;Roberts, AC;Solache, A;Schutz-Geschwender, AR;,
J. Biol. Chem. 2019
,PubMed ID 31819006
[Negative Control]
|
Angiotensin type 2 receptors: Role in aging and neuroinflammation in the substantia nigra.
,null,
Brain, behavior, and immunity
,PubMed ID 31863823
|
Mitragynine, an euphoric compound inhibits hERG1a/1b channel current and upregulates the complexation of hERG1a-Hsp90 in HEK293-hERG1a/1b cells
,null,
Scientific Reports
,PubMed ID 31874991
|
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma
,null,
OncoTargets and therapy
,PubMed ID 31807004
|
Functionalization of the TMEM175 p.M393T variant as a risk factor for Parkinson disease
,null,
Human Molecular Genetics
,PubMed ID 31261387
|
The ubiquitin-like modifier FAT10 interferes with SUMO activation
,null,
Nature Communications
,PubMed ID 31575873
|
Interferon γ and α Have Differential Effects on SAMHD1, a Potent Antiviral Protein, in Feline Lymphocytes
,null,
Viruses
,PubMed ID 31600877
|
CD200 Induces Epithelial-to-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma via β-Catenin-Mediated Nuclear Translocation
,null,
Cancers
,PubMed ID 31627350
|
Daratumumab treatment for therapy-refractory anti-CASPR2 encephalitis.
,null,
Journal of neurology
,PubMed ID 31630242
|
TMEM70 facilitates biogenesis of mammalian ATP synthase by promoting subunit c incorporation into the rotor structure of the enzyme.
,null,
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
,PubMed ID 31652072
|
A novel and potent brain penetrant inhibitor of extracellular vesicle release, et al. A novel and potent brain penetrant inhibitor of extracellular vesicle release
,null,
British Journal of Pharmacology
,PubMed ID 31273753
|
ALPPL2 Is a Potential Diagnostic Biomarker for Pancreatic Cancer-Derived Extracellular Vesicles
,null,
Molecular Therapy. Methods & Clinical Development
,PubMed ID 31687420
|
The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis
,null,
PLoS Pathogens
,PubMed ID 31181121
|
Hyaluronan synthase 2âÂÂmediated hyaluronan production mediates Notch1 activation and liver fibrosis
,null,
Science translational medicine
,PubMed ID 31189722
|
GGTase3 is a Newly Identified Geranylgeranyltransferase Targeting a Ubiquitin Ligase
,null,
Nature structural & molecular biology
,PubMed ID 31209342
|
miR-892b Inhibits Hypertrophy by Targeting KLF10 in the Chondrogenesis of Mesenchymal Stem Cells
,null,
Molecular Therapy. Nucleic Acids
,PubMed ID 31284128
|
ERp18 regulates activation of ATF6α during unfolded protein response
,null,
The EMBO Journal
,PubMed ID 31368601
|
C53: A Novel Particulate Guanylyl Cyclase B Receptor Activator That Has Sustained Activity In Vivo With Anti-Fibrotic Actions in Human Cardiac and Renal Fibroblasts
,null,
Journal of molecular and cellular cardiology
,PubMed ID 30954448
|
F-Box/WD Repeat Domain-Containing 7 Induces Chemotherapy Resistance in Colorectal Cancer Stem Cells
,null,
Cancers
,PubMed ID 31067777
|
UBAP2L arginine methylation by PRMT1 modulates stress granule assembly
,null,
Cell Death and Differentiation
,PubMed ID 31114027
|
Cbl interacts with multiple E2s in vitro and in cells
,null,
PLoS ONE
,PubMed ID 31120930
|
Asporin Restricts Mesenchymal Stromal Cell Differentiation, Alters the Tumor Microenvironment, and Drives Metastatic Progression
,null,
Cancer research
,PubMed ID 31123087
|
Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
,null,
PLoS Genetics
,PubMed ID 31125343
|
Leucine zipper and ICAT domain containing (LZIC) protein regulates cell cycle transitions in response to ionizing radiation
,null,
Cell Cycle
,PubMed ID 30973299
|
MicroRNA-181c Inhibits Interleukin-6-mediated Beta Cell Apoptosis by Targeting TNF-α Expression
,null,
Molecules
,PubMed ID 30974824
|
Caveats and Pitfalls of SOX1 Autoantibody Testing With a Commercial Line Blot Assay in Paraneoplastic Neurological Investigations
,null,
Frontiers in Immunology
,PubMed ID 31031763
|
Deletion of Sulfonylurea Receptor 2 in the Adult Myocardium Enhances Cardiac Glucose Uptake and Is Cardioprotective
,null,
JACC: Basic to Translational Science
,PubMed ID 31061927
|
Comparing small urinary extracellular vesicle purification methods with a view to RNA sequencing-Enabling robust and non-invasive biomarker research
,Mussack, V;Wittmann, G;Pfaffl, MW;,
Biomol Detect Quantif 2019
,PubMed ID 31194192
[Negative Control]
|
ERα upregulates the expression of long non-coding RNA LINC00472 which suppresses the phosphorylation of NF-κB in breast cancer
,null,
Breast cancer research and treatment
,PubMed ID 30830488
|
Hedgehog signaling in the airway epithelium of patients with chronic obstructive pulmonary disease
,null,
Scientific Reports
,PubMed ID 30833624
|
Expression and Characterization of Human Fragile X Mental Retardation Protein Isoforms and Interacting Proteins in Human Cells
,null,
Proteomics Insights
,PubMed ID 30853789
|
DNA polymerase ι is acetylated in response to SN2 alkylating agents
,null,
Scientific Reports
,PubMed ID 30886224
|
KRAS G12D or G12V Mutation in Human Brain Arteriovenous Malformations.
,null,
World neurosurgery
,PubMed ID 30902772
|
Discovery of covalent CDK14 inhibitors with pan-TAIRE family specificity
,null,
Cell chemical biology
,PubMed ID 30930164
|
Muscle A-kinase–anchoring protein-β–bound calcineurin toggles active and repressive transcriptional complexes of myocyte enhancer factor 2D
,null,
The Journal of Biological Chemistry
,PubMed ID 30523159
|
Angiopoietin-1 haploinsufficiency affects the endothelial barrier and causes hereditary angioedema.
,null,
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
,PubMed ID 30689269
|
AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells
,null,
The Journal of steroid biochemistry and molecular biology
,PubMed ID 30769091
|
Thioredoxin system as a gatekeeper in caspase-6 activation and nuclear lamina integrity: Implications for Alzheimer's disease.
,null,
Free radical biology medicine
,PubMed ID 30769159
|
Annexin II Light Chain p11 Interacts With ENaC to Increase Functional Activity at the Membrane
,null,
Frontiers in Physiology
,PubMed ID 30800070
|
Mutations in ILK, encoding integrin linked kinase, are associated with arrhythmogenic cardiomyopathy
,null,
Translational research : the journal of laboratory and clinical medicine
,PubMed ID 30802431
|
RNA binding antagonizes neurotoxic phase transitions of TDP-43.
,null,
Neuron
,PubMed ID 30826182
|
Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-gated, Inwardly-rectifying, Potassium (GIRK) Channels
,null,
ACS chemical neuroscience
,PubMed ID 30136838
|
Abundant glutamic acid decarboxylase (GAD)-reactive B cells in gad-antibody-associated neurological disorders.
,null,
Annals of neurology
,PubMed ID 30635933
|
Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration.
,null,
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
,PubMed ID 31050282
|
Plastin 3 influences bone homeostasis through regulation of osteoclast activity.
,null,
Human molecular genetics
,PubMed ID 30204862
|
Garcinia Multiflora Inhibits FPR1-Mediated Neutrophil Activation and Protects Against Acute Lung Injury.
,null,
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
,PubMed ID 30562761
|
Transmembrane protein 100 is expressed in neurons and glia of dorsal root ganglia and is reduced after painful nerve injury
,null,
Pain Reports
,PubMed ID 30801043
|
Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein
,null,
The Journal of Neuroscience
,PubMed ID 30249802
|
LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory
,null,
Brain
,PubMed ID 30346486
|
Histone-Mimetic Gold Nanoparticles as Versatile Scaffolds for Gene Transfer and Chromatin Analysis
,null,
Bioconjugate chemistry
,PubMed ID 30350573
|
Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes
,null,
Science Advances
,PubMed ID 30474060
|
Highly Potent 17β-HSD2 Inhibitors with a Promising Pharmacokinetic Profile for Targeted Osteoporosis Therapy.
,null,
Journal of medicinal chemistry
,PubMed ID 30480443
|
Chronic Inflammatory Demyelinating Polyneuropathy With Concurrent Membranous Nephropathy: An Anti-paranode and Podocyte Protein Antibody Study and Literature Survey
,null,
Frontiers in Neurology
,PubMed ID 30538665
|
Cancer/testis Antigen MAGEA3 Interacts with STAT1 and Remodels the Tumor Microenvironment
,null,
International Journal of Medical Sciences
,PubMed ID 30588194
|
Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling
,null,
The Journal of Biological Chemistry
,PubMed ID 30126842
|
Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism
,null,
The Journal of Cell Biology
,PubMed ID 30154187
|
Bacterial lipoproteins constitute the TLR2-stimulating activity of Serum Amyloid A
,null,
Journal of immunology (Baltimore, Md. : 1950)
,PubMed ID 30158125
|
Structure-Based Identification of Potent Natural Product Chemotypes as Cannabinoid Receptor 1 Inverse Agonists
,null,
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
,PubMed ID 30322136
|
Next-generation sequencing identified SPATC1L as a possible candidate gene for both early-onset and age-related hearing loss
,null,
European Journal of Human Genetics
,PubMed ID 30177775
|
Association of the IP3R to STIM1 provides a reduced intraluminal calcium microenvironment, resulting in enhanced store-operated calcium entry
,null,
Scientific Reports
,PubMed ID 30185837
|
Loss-of-function mutations in caspase recruitment domain-containing protein 14 (CARD14) are associated with a severe variant of atopic dermatitis.
,null,
The Journal of allergy and clinical immunology
,PubMed ID 30248356
|
PUM1 and PUM2 exhibit different modes of regulation for SIAH1 that involve cooperativity with NANOS paralogues.
,null,
Cellular and molecular life sciences : CMLS
,PubMed ID 30269240
|
Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8
,Merriman, C;Li, H;Li, H;Fu, D;,
J. Biol. Chem. 2018
,PubMed ID 30181214
[Negative Control]
|
Periostin promotes liver fibrogenesis by activating lysyl oxidase in hepatic stellate cells
,null,
The Journal of Biological Chemistry
,PubMed ID 29941453
|
Neuronatin regulates pancreatic β cell insulin content and secretion
,null,
The Journal of Clinical Investigation
,PubMed ID 29864031
|
Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier-Mediated Process.
,null,
Molecular pharmaceutics
,PubMed ID 29944835
|
Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress
,null,
Nucleic Acids Research
,PubMed ID 29850896
|
KIAA0100 Modulates Cancer Cell Aggression Behavior of MDA-MB-231 through Microtubule and Heat Shock Proteins
,null,
Cancers
,PubMed ID 29867023
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Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1.
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Cancer letters
,PubMed ID 29964205
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Alternative utrophin mRNAs contribute to phenotypic differences between dystrophin‐deficient mice and Duchenne muscular dystrophy
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Febs Letters
,PubMed ID 29772070
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Dysregulation of the MiR-449b target TGFBI alters the TGFβ pathway to induce cisplatin resistance in nasopharyngeal carcinoma
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Oncogenesis
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Lethal influenza in two related adults with inherited GATA-2 deficiency
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Journal of clinical immunology
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Upregulation of Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Mediates the Reversal Effect of Verapamil on Chemo-Resistance to Adriamycin of Hepatocellular Carcinoma
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Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
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Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach
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mAbs
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KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses.
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Cell host microbe
,PubMed ID 29681460
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Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1.
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Molecular immunology
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Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase
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Oncotarget
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CRRL269: a novel designer and renal-enhancing pGC-A peptide activator
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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology
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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
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Nature
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The Role of AIRE in the Immunity Against Candida Albicans in a Model of Human Macrophages
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Frontiers in Immunology
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Partial growth hormone insensitivity and dysregulatory immune disease associated with de novo germline activating STAT3 mutations
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Molecular and cellular endocrinology
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NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus
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eLife
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A glucose-responsive insulin therapy protects animals against hypoglycemia
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JCI Insight
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A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7
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PLoS Pathogens
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Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain
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Frontiers in Molecular Neuroscience
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LAG-3 in non-small cell lung cancer: expression in primary tumors and metastatic lymph nodes is associated with improved survival
,Hald, SM;Rakaee, M;Martinez, I;Richardsen, E;Al-Saad, S;Paulsen, E;Blix, ES;,
Clinical Lung Cancer 2017
[HEK293 cell lysate]
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Paracoccidioidomycosis Associated With a Heterozygous STAT4 Mutation and Impaired IFN-γ Immunity.
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The Journal of infectious diseases
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Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury.
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Cell stem cell
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Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters
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Oncotarget
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An unexpected protein interaction promotes drug resistance in leukemia
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Nature Communications
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HAX-1 Regulates SERCA2a Oxidation and Degradation
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Journal of molecular and cellular cardiology
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Febrile infection-related epilepsy syndrome (FIRES) with super-refractory status epilepticus revealing autoimmune encephalitis due to GABAAR antibodies.
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European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
,PubMed ID 29203057
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The expression profile of sterile alpha motif and histidine-aspartate domain-containing protein 1 (SAMHD1) in feline tissues.
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Veterinary immunology and immunopathology
,PubMed ID 29249320
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A missense mutation in SLC26A3 is associated with human male subfertility and impaired activation of CFTR
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Scientific Reports
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Regulation of the epithelial Na+ channel by paraoxonase-2
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The Journal of Biological Chemistry
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The intracellular angiotensin system buffers deleterious effects of the extracellular paracrine system
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Cell Death & Disease
,PubMed ID 28880266
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RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling
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Endocrinology
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miR-23a Regulates Cardiomyocyte Apoptosis by Targeting Manganese Superoxide Dismutase
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Molecules and Cells
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Association of the PLCB1 gene with drug dependence
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Scientific Reports
,PubMed ID 28860459
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Yersinia pestis YopK Inhibits Bacterial Adhesion to Host Cells by Binding to the Extracellular Matrix Adaptor Protein Matrilin-2
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Infection and Immunity
,PubMed ID 28533472
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Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB.
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Free radical biology medicine
,PubMed ID 28712859
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Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis
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PLoS Pathogens
,PubMed ID 28715499
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RIG-I expression in perifascicular myofibers is a reliable biomarker of dermatomyositis
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Arthritis Research & Therapy
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CTLA-4 expression in the non-small cell lung cancer patient tumor microenvironment: diverging prognostic impact in primary tumors and lymph node metastases
,Paulsen, EE;Kilvaer, TK;Rakaee, M;Richardsen, E;Hald, SM;Andersen, S;Busund, LT;Bremnes, RM;Donnem, T;,
Cancer Immunol. Immunother. 2017
,PubMed ID 28707078
[Negative Control]
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MicroRNA-34a suppresses colorectal cancer metastasis by regulating Notch signaling
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Oncology Letters
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Insulin signaling via the PI3-kinase/Akt pathway regulates airway glucose uptake and barrier function in a CFTR-dependent manner
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American Journal of Physiology - Lung Cellular and Molecular Physiology
,PubMed ID 28213469
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AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation
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The Journal of Biological Chemistry
,PubMed ID 28330873
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PPPDE1 is a novel deubiquitinase belonging to a cysteine isopeptidase family.
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Biochemical and biophysical research communications
,PubMed ID 28483520
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Fibulin-3 promotes muscle-invasive bladder cancer.
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Oncogene
,PubMed ID 28504717
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Transient receptor potential vanilloid 5 (TRPV5), a highly Ca2+ -selective TRP channel in the rat brain: relevance to neuroendocrine regulation.
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Journal of neuroendocrinology
,PubMed ID 28235149
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Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client.
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Biochemical and biophysical research communications
,PubMed ID 28416388
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Inflammatory Effects of Menthol vs. Non-menthol Cigarette Smoke Extract on Human Lung Epithelial Cells: A Double-Hit on TRPM8 by Reactive Oxygen Species and Menthol
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Frontiers in Physiology
,PubMed ID 28496415
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Copper transporter 1 in human colorectal cancer cell lines: Effects of endogenous and modified expression on oxaliplatin cytotoxicity.
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Journal of inorganic biochemistry
,PubMed ID 28551160
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MC4R-dependent suppression of appetite by bone-derived lipocalin 2
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Nature
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GLUT4 Is Not Necessary for Overload-Induced Glucose Uptake or Hypertrophic Growth in Mouse Skeletal Muscle
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Diabetes
,PubMed ID 28279980
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ORAI2 modulates store-operated calcium entry and T cell-mediated immunity
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Nature Communications
,PubMed ID 28294127
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The prognostic role of immune checkpoint markers programmed cell death protein 1 (PD-1) and programmed death ligand 1 (PD-L1) in a large, multicenter prostate cancer cohort
,Ness, N;Andersen, S;Khanehkenari, MR;Nordbakken, CV;Valkov, A;Paulsen, E;Nordby, Y;Bremnes, RM;Donnem, T;Busund, L;Richardsen, E;,
oncotarget 2016
,PubMed ID 28460462
[Negative Control]
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Quantitative Impact of Plasma Clearance and Down-regulation on GLP-1 Receptor Molecular Imaging
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Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging
,PubMed ID 26194012
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Glial fibrillary acidic protein immunoglobulin G as biomarker of autoimmune astrocytopathy: Analysis of 102 patients.
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Annals of neurology
,PubMed ID 28120349
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Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination
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Nature Communications
,PubMed ID 28176781
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IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes
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Nature Communications
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Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1.
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Free radical biology medicine
,PubMed ID 28232203
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A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy
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Nephrology Dialysis Transplantation
,PubMed ID 28339911
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Different Phenotypes of the Two Chinese Probands with the Same c.889G > A (p.C162Y) Mutation in COCH Gene Verify Different Mechanisms Underlying Autosomal Dominant Nonsyndromic Deafness 9
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PLoS ONE
,PubMed ID 28099493
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A quantized mechanism for activation of pannexin channels
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Nature Communications
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Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis
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PLoS Genetics
,PubMed ID 27923061
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Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy.
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Science translational medicine
,PubMed ID 28003546
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Activation of the Ca2+-sensing receptors increases currents through inward rectifier K+ channels via activation of phosphatidylinositol 4-kinase
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Pflugers Archiv
,PubMed ID 27838849
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Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays.
,null,
Free radical biology medicine
,PubMed ID 27863990
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Immunogenicity and transmission reducing potency of Pfs48/45 and Pfs25 encoded by DNA vaccines administered by intramuscular electroporation
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Vaccine
,PubMed ID 27912985
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Assessing PD-L1 and PD-1 in Non-Small Cell Lung Cancer (NSCLC): a Novel Immunoscore Approach
,Paulsen, EE;Kilvaer, TK;Khanehkenari, MR;Saad, SA;Hald, SM;Andersen, S;Richardsen, E;Ness, N;Busund, LT;Bremnes, RM;Donnem, T;,
Clinical Lung Cancer 2016
,PubMed ID 27816392
[negative control]
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The oxoglutarate receptor 1 (OXGR1) modulates pressure overload-induced cardiac hypertrophy in mice
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Biochemical and Biophysical Research Communications
,PubMed ID 27693579
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Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone
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Scientific Reports
,PubMed ID 27752123
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Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration
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Cell Death & Disease
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Molecular changes in appearance of a cancer cell among normal HEK293T cells.
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Journal of bioscience and bioengineering
,PubMed ID 27777049
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MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts
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RMD Open
,PubMed ID 27843576
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Perturbation of redox balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells.
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Free radical biology medicine
,PubMed ID 27693380
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DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes
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The Journal of Experimental Medicine
,PubMed ID 27455952
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Enzyme overexpression – an exercise toward understanding regulation of heparan sulfate biosynthesis
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Scientific Reports
,PubMed ID 27511124
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Investigating the Molecular Basis of PPCD3: Characterization of ZEB1 Regulation of COL4A3 Expression
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Investigative Ophthalmology & Visual Science
,PubMed ID 27537263
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LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex
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Structure(London, England:1993)
,PubMed ID 27265849
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LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis
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Oncotarget
,PubMed ID 27323408
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Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins
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Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 27325759
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An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron
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Science translational medicine
,PubMed ID 27412786
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ARID4B is a good biomarker to predict tumour behaviour and decide WHO grades in gliomas and meningiomas
,Tsai, WC;Hueng, DY;Nieh, S;Gao, HW;,
J. Clin. Pathol. 2016
,PubMed ID 27451434
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Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue
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Scientific Reports
,PubMed ID 27257141
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Characterization of GPR101 transcript structure and expression patterns
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Journal of molecular endocrinology
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Arylsulfatase B Mediates the Sulfonation-Transport Interplay in Human Embryonic Kidney 293 Cells Overexpressing Sulfotransferase 1A3.
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Drug metabolism and disposition: the biological fate of chemicals
,PubMed ID 27325375
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Preclinical profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats
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Psychopharmacology
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Pharmacological Modulations of the Serotonergic System in a Cell-Model of Familial Alzheimer's Disease.
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Journal of Alzheimer's disease : JAD
,PubMed ID 27163814
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Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging
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Oncotarget
,PubMed ID 27167199
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Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H.
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Neuropharmacology
,PubMed ID 27245500
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FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice
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Nature Communications
,PubMed ID 27066907
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TRPV3 expression and vasodilator function in isolated uterine radial arteries from non-pregnant and pregnant rats.
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Vascular pharmacology
,PubMed ID 27073026
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Growing Mouse Oocytes Transiently Activate Folate Transport via Folate Receptors As They Approach Full Size 1
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Biology of Reproduction
,PubMed ID 27122634
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Extracellular HSP110 skews macrophage polarization in colorectal cancer
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Oncoimmunology
,PubMed ID 27622020
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Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5’-Flanking Region
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PLoS ONE
,PubMed ID 26999742
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The angiotensin receptor-associated protein Atrap is a stimulator of the cardiac Ca2+-ATPase SERCA2a.
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Cardiovascular research
,PubMed ID 27015675
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MicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytes
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Arthritis & rheumatology (Hoboken, N.J.)
,PubMed ID 25385442
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Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions
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Molecular pharmaceutics
,PubMed ID 26750564
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Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate
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PLoS ONE
,PubMed ID 26840340
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The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation
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Nature Communications
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Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
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Cancer immunology research
,PubMed ID 26842750
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Stronger Uricosuric Effects of the Novel Selective URAT1 Inhibitor UR-1102 Lowered Plasma Urate in Tufted Capuchin Monkeys to a Greater Extent than Benzbromarone.
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The Journal of pharmacology and experimental therapeutics
,PubMed ID 26907620
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Increased internalization of complement inhibitor CD59 may contribute to endothelial inflammation in obstructive sleep apnea
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Science translational medicine
,PubMed ID 26738794
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Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A
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Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 26621751
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Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target
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PLoS Pathogens
,PubMed ID 26624286
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Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme
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PLoS ONE
,PubMed ID 26637123
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Mutations Preventing Regulated Exon Skipping in MET Cause Osteofibrous Dysplasia
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American Journal of Human Genetics
,PubMed ID 26637977
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Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities
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PLoS Genetics
,PubMed ID 26709516
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Acoustofluidic Chemical Waveform Generator and Switch
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Analytical Chemistry
,PubMed ID 25405550
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Pinosylvin Inhibits TRPA1-Induced Calcium Influx In Vitro and TRPA1-Mediated Acute Paw Inflammation In Vivo.
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Basic clinical pharmacology toxicology
,PubMed ID 26335783
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Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription
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Nucleic Acids Research
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The Cyclooctadepsipeptide Anthelmintic Emodepside Differentially Modulates Nematode, Insect and Human Calcium-Activated Potassium (SLO) Channel Alpha Subunits
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PLoS Neglected Tropical Diseases
,PubMed ID 26437177
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WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma.
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Cancer research
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NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1
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The Journal of Experimental Medicine
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Prediction and validation of enzyme and transporter off-targets for metformin
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Journal of pharmacokinetics and pharmacodynamics
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Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1
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PLoS ONE
,PubMed ID 26378785
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Reciprocal regulation between sirtuin-1 and angiotensin-II in the substantia nigra: implications for aging and neurodegeneration
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Oncotarget
,PubMed ID 26384348
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CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium
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Scientific Reports
,PubMed ID 26404741
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The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4
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The Journal of Neuroscience
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Development of a Surface Plasmon Resonance Assay for the Characterization of Small-Molecule Binding Kinetics and Mechanism of Binding to Kynurenine 3-Monooxygenase.
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Assay and drug development technologies
,PubMed ID 26292018
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Towards the evaluation in an animal disease model: Fluorinated 17β-HSD1 inhibitors showing strong activity towards both the human and the rat enzyme.
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European journal of medicinal chemistry
,PubMed ID 26322835
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SPSB1, a Novel Negative Regulator of the Transforming Growth Factor-β Signaling Pathway Targeting the Type II Receptor *
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The Journal of Biological Chemistry
,PubMed ID 26032413
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Evaluation of the Impact of Codon Optimization and N-Linked Glycosylation on Functional Immunogenicity of Pfs25 DNA Vaccines Delivered by In Vivo Electroporation in Preclinical Studies in Mice
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Clinical and Vaccine Immunology : CVI
,PubMed ID 26135972
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A CD44 specific peptide developed by phage display for targeting gastric cancer.
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Biotechnology letters
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9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate
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Nature Communications
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Mutations in JMJD1C are involved in Rett syndrome and intellectual disability
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Genetics in Medicine
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Mammalian Bcnt/Cfdp1, a potential epigenetic factor characterized by an acidic stretch in the disordered N-terminal and Ser250 phosphorylation in the conserved C-terminal regions
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Bioscience Reports
,PubMed ID 26182435
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Whole Exome Sequencing Identified MCM2 as a Novel Causative Gene for Autosomal Dominant Nonsyndromic Deafness in a Chinese Family
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PLoS ONE
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Site-Specific Glycan Microheterogeneity of Inter-Alpha-Trypsin Inhibitor Heavy Chain H4
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Journal of Proteome Research
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Integrated Approaches for Analyzing U1-70K Cleavage in Alzheimer’s Disease
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Journal of Proteome Research
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γ-secretase directly sheds the survival receptor BCMA from plasma cells
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Nature Communications
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LECT2 induces atherosclerotic inflammatory reaction via CD209 receptor-mediated JNK phosphorylation in human endothelial cells.
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Metabolism: clinical and experimental
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Lipoprotein(a) Catabolism Is Regulated by Proprotein Convertase Subtilisin/Kexin Type 9 through the Low Density Lipoprotein Receptor *
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The Journal of Biological Chemistry
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Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site.
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Free radical biology medicine
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LRIG1 extracellular domain: structure and function analysis.
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Journal of molecular biology
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Antibodies to Inhibitory Synaptic Proteins in Neurological Syndromes Associated with Glutamic Acid Decarboxylase Autoimmunity
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PLoS ONE
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Dissecting Antibodies with Regards to Linear and Conformational Epitopes
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PLoS ONE
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Urate Crystal Induced Inflammation and Joint Pain Are Reduced in Transient Receptor Potential Ankyrin 1 Deficient Mice – Potential Role for Transient Receptor Potential Ankyrin 1 in Gout
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PLoS ONE
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Analytical platform evaluation for quantification of ERG in prostate cancer using protein and mRNA detection methods
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Journal of Translational Medicine
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Phosphorylation and Inactivation of Glycogen Synthase Kinase 3β (GSK3β) by Dual-specificity Tyrosine Phosphorylation-regulated Kinase 1A (Dyrk1A) *
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The Journal of Biological Chemistry
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miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6
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Molecular and Cellular Pediatrics
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Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats.
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American journal of physiology. Regulatory, integrative and comparative physiology
,PubMed ID 25519731
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Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget
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Oncotarget
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Checkpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress
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Nucleic Acids Research
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Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats.
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Neurobiology of aging
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Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion
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Sensors and actuators. B, Chemical
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MDR1 Transporter Protects Against Paraquat-Induced Toxicity in Human and Mouse Proximal Tubule Cells
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Toxicological Sciences
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Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD)
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Blood
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Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?
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Human immunology
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RNA-Processing Protein TDP-43 Regulates FOXO-Dependent Protein Quality Control in Stress Response
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PLoS Genetics
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Structural Basis of the Proteolytic and Chaperone Activity of Chlamydia trachomatis CT441
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Journal of Bacteriology
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CEACAM1 regulates TIM–3–mediated tolerance and exhaustion
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Nature
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Cortactin autoantibodies in myasthenia gravis.
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Autoimmunity reviews
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CAPN5 gene silencing by short hairpin RNA interference
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BMC Research Notes
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Adeno-associated virus-RNAi of GlyRα1 and characterization of its synapse-specific inhibition in OFF alpha transient retinal ganglion cells
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Journal of Neurophysiology
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c-Jun transcriptionally regulates alpha 1, 2-fucosyltransferase 1 (FUT1) in ovarian cancer.
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Biochimie
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MDA-9/Syntenin regulates differentiation and angiogenesis programs in head and neck squamous cell carcinoma
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Oncoscience
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Ageing related periostin expression increase from cardiac fibroblasts promotes cardiomyocytes senescent.
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Biochemical and biophysical research communications
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A roadmap to evaluate the proteome-wide selectivity of covalent kinase inhibitors
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Nature chemical biology
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The Epithelial Sodium Channel γ-Subunit Is Processed Proteolytically in Human Kidney
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Journal of the American Society of Nephrology : JASN
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The DNA sensor, cyclic GMP-AMP synthase (cGAS) is essential for induction of IFN beta during Chlamydia trachomatis infection
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Journal of immunology (Baltimore, Md. : 1950)
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Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4
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Cancer research
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Glycerol-3-Phosphate Acyltranferase-2 Behaves as a Cancer Testis Gene and Promotes Growth and Tumorigenicity of the Breast Cancer MDA-MB-231 Cell Line
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PLoS ONE
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Tumor Necrosis Factor (TNF)-α Induction of CXCL10 in Endothelial Cells Requires Protein Arginine Methyltransferase 5 (PRMT5)-mediated Nuclear Factor (NF)-κB p65 Methylation *
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Validation of a Hypoxia-Inducible Factor-1α Specimen Collection Procedure and Quantitative ELISA in Solid Tumor Tissues
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Analytical biochemistry
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Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
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Nature
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A novel NREM and REM parasomnia with sleep breathing disorder associated with antibodies against IgLON5: a case series, pathological features, and characterization of the antigen
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Lancet neurology
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Juno is the egg Izumo receptor and is essential for mammalian fertilisation
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Nature
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TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination.
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A Novel Protein Is Lower Expressed in Renal Cell Carcinoma
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The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina
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The Journal of comparative neurology
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Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate
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Amino acids
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Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers), Garbage in, garbage out: A critical evaluation of strategies used for validation of immunohistochemical biomarkers
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Molecular Oncology
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Discovery Of An Orexin Receptor Positive Potentiator
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Chemical science (Royal Society of Chemistry : 2010)
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Divergent Label-free Cell Phenotypic Pharmacology of Ligands at the Overexpressed ?2-Adrenergic Receptors
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Scientific Reports
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Lysine biotinylation and methionine oxidation in the heat shock protein HSP60 synergize in the elimination of reactive oxygen species in human cell cultures
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The Journal of nutritional biochemistry
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Envelope Glycoprotein Binding to the Integrin α4β7 Is Not a General Property of Most HIV-1 Strains
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Journal of Virology
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Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway.
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Cell stem cell
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β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency.
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Cellular signalling
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Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis
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Nature medicine
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Chorein, the protein responsible for chorea-acanthocytosis, interacts with β-adducin and β-actin.
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Biochemical and biophysical research communications
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A novel human-derived antibody against NY-ESO-1 improves the efficacy of chemotherapy
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Cancer Immunity
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An X-Linked Cobalamin Disorder Caused by Mutations in Transcriptional Coregulator HCFC1
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American Journal of Human Genetics
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Non-Catalytic Site HIV-1 Integrase Inhibitors Disrupt Core Maturation and Induce a Reverse Transcription Block in Target Cells
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Disorders with similar clinical phenotypes reveal underlying genetic interaction: SATB2 acts as an activator of the UPF3B gene
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Functional Properties of Rare Missense Variants of Human CDH13 Found in Adult Attention Deficit/Hyperactivity Disorder (ADHD) Patients
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Soluble Variants of Human Recombinant Glutaminyl Cyclase
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PLoS ONE
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The C- and N-terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels
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The Journal of Physiology
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Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer
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British Journal of Cancer
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Modulation of OATP1B-type Transporter Function Alters Cellular Uptake and Disposition of Platinum Chemotherapeutics
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Molecular cancer therapeutics
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Protein Kinase A and Phosphodiesterase-4D3 Binding to Coding Polymorphisms of Cardiac Muscle Anchoring Protein (mAKAP)
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Journal of molecular biology
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Tumor suppressor role of the CL2/DRO1/CCDC80 gene in thyroid carcinogenesis.
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The Journal of clinical endocrinology and metabolism
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Microplate-compatible total internal reflection fluorescence microscopy for receptor pharmacology
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Applied Physics Letters
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A Cholesterol Recognition Amino Acid Consensus Domain in GP64 Fusion Protein Facilitates Anchoring of Baculovirus to Mammalian Cells
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Journal of Virology
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GAS6 Receptor Status Is Associated with Dormancy and Bone Metastatic Tumor Formation
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PLoS ONE
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Antibody Repertoire in Paraneoplastic Cerebellar Degeneration and Small Cell Lung Cancer
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PLoS ONE
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Development of a coordinated allo T cell and auto B cell response against autosomal PTK2B after allogeneic hematopoietic stem cell transplantation
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Haematologica
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Isolation and identification of cell-specific microRNAs targeting a messenger RNA using a biotinylated anti-sense oligonucleotide capture affinity technique
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Nucleic Acids Research
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Holocarboxylasesynthetase interacts physically with euchromatic histone-lysine N-methyltransferase, linking histone biotinylation with methylation events *
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The Journal of nutritional biochemistry
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Ubiquitin mediates the physical and functional interaction between human DNA polymerases ? and ?
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Nucleic Acids Research
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Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes
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Journal of Cell Science
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Cross-talk Among RNA Polymerase II Kinases Modulates C-terminal Domain Phosphorylation *
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The Journal of Biological Chemistry
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Hkat, a novel nutritionally regulated transmembrane protein in adipose tissues
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Scientific Reports
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Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation
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Cancer cell
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Using protein microarray technology to screen anti-ERCC1 monoclonal antibodies for specificity and applications in pathology
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BMC Biotechnology
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Nrac, a Novel Nutritionally-Regulated Adipose and Cardiac-Enriched Gene
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PLoS ONE
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Peroxidasin Forms Sulfilimine Chemical Bonds Using Hypohalous Acids In Tissue Genesis
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Nature chemical biology
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Molecular Pharmacology
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Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel
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Clinical cancer research : an official journal of the American Association for Cancer Research
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Reversible Lysine Acetylation Regulates Activity of Human Glycine N-Acyltransferase-like 2 (hGLYATL2)
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The Journal of Biological Chemistry
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SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways
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The Journal of Cell Biology
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CD70 Expression Patterns in Renal Cell Carcinoma
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Human pathology
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SS18 Together with Animal-Specific Factors Defines Human BAF-Type SWI/SNF Complexes
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PLoS ONE
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Analysis of antibodies to surface epitopes of contactin-2 in multiple sclerosis
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Journal of neuroimmunology
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Gated regulation of CRAC channel ion selectivity by STIM1
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Nature
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Functionally Recurrent Rearrangements of the MAST Kinase and Notch Gene Families in Breast Cancer
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Nature Medicine
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Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen
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Blood
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Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase
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Nature Cell Biology
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Regulation of Pou4f3 Gene Expression in Hair Cells by 5' DNA in Mice
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Neuroscience
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Substance P Induces Rapid and Transient Membrane Blebbing in U373MG Cells in a p21-Activated Kinase-Dependent Manner
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PLoS ONE
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A functional NR4A nuclear receptor DNA-binding domain is required for organ development in C. elegans
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Genesis (New York, N.Y. : 2000)
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Dimerization of the DYT6 dystonia protein, THAP1, requires residues within the coiled-coil domain
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Journal of neurochemistry
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Angelman Syndrome Protein UBE3A Interacts with Primary Microcephaly Protein ASPM, Localizes to Centrosomes and Regulates Chromosome Segregation
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PLoS ONE
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Mitofusin 2 Regulates STIM1 Migration from the Ca2+ Store to the Plasma Membrane in Cells with Depolarized Mitochondria *
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The Journal of Biological Chemistry
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Cocaine hijacks sigma-1 receptor to initiate induction of ALCAM: Implication for increased monocyte adhesion and migration in the central nervous system
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The Journal of neuroscience : the official journal of the Society for Neuroscience
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Regulator of G Protein Signaling 5 Is Highly Expressed in Parathyroid Tumors and Inhibits Signaling by the Calcium-Sensing Receptor
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Molecular Endocrinology
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Mapping of the Disease Locus and Identification of ADAMTS10 As a Candidate Gene in a Canine Model of Primary Open Angle Glaucoma
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PLoS Genetics
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Ectopic Mineralization in the Middle Ear and Chronic Otitis Media with Effusion Caused by RPL38 Deficiency in the Tail-short (Ts) Mouse *
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The Journal of Biological Chemistry
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Calcium channels link the muscle-derived synapse organizer laminin ?2 to Bassoon and CAST/Erc2 to organize presynaptic active zones
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The Journal of neuroscience : the official journal of the Society for Neuroscience
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Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters
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Experimental hematology
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PHLPP1 splice variants differentially regulate AKT and PKC? signaling in hippocampal neurons: characterization of PHLPP proteins in the adult hippocampus
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Journal of neurochemistry
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Chordin-like 1 and Twisted Gastrulation 1 Regulate BMP Signaling following Kidney Injury
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Journal of the American Society of Nephrology : JASN
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Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer
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Journal of Oncology
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Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex
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Chemistry & biology
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Alpha9 nicotinic acetylcholine receptors and the treatment of pain
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Biochemical pharmacology
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Polo-like Kinase 2 (PLK2) Phosphorylates ?-Synuclein at Serine 129 in Central Nervous System *Polo-like Kinase 2 (PLK2) Phosphorylates ?-Synuclein at Serine 129 in Central Nervous System * S⃞
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The Journal of Biological Chemistry
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Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels.
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The Journal of biological chemistry
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