MAP4K3 Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA	GFP-puro
Symbol	MAP4K3
Locus ID	8491
Kit Components	KN217448G1, MAP4K3 gRNA vector 1 in pCas-Guide CRISPR vector KN217448G2, MAP4K3 gRNA vector 2 in pCas-Guide CRISPR vector KN217448-D, donor DNA containing left and right homologous arms and GFP-puro functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001270425, NM_003618
Synonyms	GLK; MAPKKKK3; MEKKK 3; MEKKK3; RAB8IPL1
Summary	This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

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