TXNIP Human Gene Knockout Kit (CRISPR)
CAT#: KN210804LP
TXNIP - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | TXNIP |
Locus ID | 10628 |
Kit Components |
KN210804G1, TXNIP gRNA vector 1 in pCas-Guide CRISPR vector KN210804G2, TXNIP gRNA vector 2 in pCas-Guide CRISPR vector KN210804LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001313972, NM_006472 |
Synonyms | ARRDC6; EST01027; HHCPA78; THIF; VDUP1 |
Summary | This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN210804 | TXNIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN210804BN | TXNIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN210804RB | TXNIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN410804 | TXNIP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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GA107279 | TXNIP CRISPRa kit - CRISPR gene activation of human thioredoxin interacting protein |
CNY 12,255.00 |