ATG5 Human Gene Knockout Kit (CRISPR)
CAT#: KN210563RB
ATG5 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | ATG5 |
Locus ID | 9474 |
Kit Components |
KN210563G1, ATG5 gRNA vector 1 in pCas-Guide CRISPR vector KN210563G2, ATG5 gRNA vector 2 in pCas-Guide CRISPR vector KN210563RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001286106, NM_001286107, NM_001286108, NM_001286111, NM_004849, NR_104402, NR_104403 |
Synonyms | APG5; APG5-LIKE; APG5L; ASP; hAPG5 |
Summary | The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
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KN210563 | ATG5 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN210563BN | ATG5 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN210563LP | ATG5 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN410563 | ATG5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
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