STING (TMEM173) Human Gene Knockout Kit (CRISPR)

CAT#: KN208418LP

TMEM173 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


TMEM173 mouse monoclonal antibody, clone OTI4H1 (formerly 4H1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TMEM173 (Myc-DDK-tagged)-Human transmembrane protein 173 (TMEM173), nuclear gene encoding mitochondrial protein
    • 10 ug

CNY 5,488.00

Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol STING
Locus ID 340061
Kit Components

KN208418G1, STING gRNA vector 1 in pCas-Guide CRISPR vector

KN208418G2, STING gRNA vector 2 in pCas-Guide CRISPR vector

KN208418LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001301738, NM_198282, NM_001367258
Synonyms ERIS; hMITA; hSTING; MITA; MPYS; NET23; SAVI; STING
Summary This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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