Mouse Angptl8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Angptl8
Locus ID	624219
Kit Components	GA218016G1, Angptl8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA218016G2, Angptl8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA218016G3, Angptl8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080940
Synonyms	EG624219; Gm6484; Rifl
Summary	Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787).[UniProtKB/Swiss-Prot Function]

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