Mouse Prr7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Prr7
Locus ID	432763
Kit Components	GA217508G1, Prr7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217508G2, Prr7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217508G3, Prr7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001030296
Synonyms	XM_484263
Summary	Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (By similarity). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:27657535). Might promote apoptosis in T cells (By similarity).[UniProtKB/Swiss-Prot Function]

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