Mouse Akap7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Akap7
Locus ID	432442
Kit Components	GA217477G1, Akap7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217477G2, Akap7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217477G3, Akap7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347460, NM_018747
Synonyms	6430401D08; AI662165; AKAP15; Akap18; BB170514
Summary	Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity).[UniProtKB/Swiss-Prot Function]

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