Mouse Flrt1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Flrt1
Locus ID	396184
Kit Components	GA217351G1, Flrt1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217351G2, Flrt1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217351G3, Flrt1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_201411
Synonyms	AW742165; D630040I23Rik
Summary	Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases (PubMed:16872596, PubMed:20421966). Promotes neurite outgrowth via FGFR1-mediated activation of downstream MAP kinases. Promotes an increase both in neurite number and in neurite length (PubMed:20421966). May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3 (PubMed:22405201).[UniProtKB/Swiss-Prot Function]

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