Mouse Rrm2b activation kit by CRISPRa
CAT#: GA217266
Rrm2b CRISPRa kit - CRISPR gene activation of mouse ribonucleotide reductase M2 B (TP53 inducible)
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Rrm2b |
Locus ID | 382985 |
Kit Components | GA217266G1, Rrm2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217266G2, Rrm2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217266G3, Rrm2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_199476, NM_001357022, NM_001357023 |
Synonyms | p53R2 |
Summary | Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN515140 | Rrm2b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |