Mouse Zfp488 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zfp488
Locus ID	382867
Kit Components	GA217264G1, Zfp488 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217264G2, Zfp488 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217264G3, Zfp488 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001013777
Synonyms	Gm1206; Znf488
Summary	Transcriptional repressor (PubMed:16908628). Plays a role in oligodendrocyte differentiation, together with OLIG2 (PubMed:16908628, PubMed:22355521). Mediates Notch signaling-activated formation of oligodendrocyte precursors (PubMed:16908628). Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury (PubMed:22355521).[UniProtKB/Swiss-Prot Function]

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