Mouse Fbxw15 activation kit by CRISPRa
CAT#: GA217222
Fbxw15 CRISPRa kit - CRISPR gene activation of mouse F-box and WD-40 domain protein 15
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Fbxw15 |
Locus ID | 382105 |
Kit Components | GA217222G1, Fbxw15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217222G2, Fbxw15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217222G3, Fbxw15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_199036 |
Synonyms | Fbxo12J |
Summary | Substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes KAT7 ubiquitination and subsequent degradation in collaboration with MAP2K1 kinase, leading to reduced histone H3K14 acetylation and increased cell proliferation.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN505844 | Fbxw15 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |