Mouse Adgrg5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adgrg5
Locus ID	382045
Kit Components	GA217210G1, Adgrg5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217210G2, Adgrg5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217210G3, Adgrg5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033468, NM_001145972
Synonyms	Gm1109; Gpr114; PGR27
Summary	Adhesion G protein-coupled receptor (GPCR). Transduces intracellular signals through coupling to guanine nucleotide-binding protein G(s) subunit alpha and activation of adenylate cyclase pathway (PubMed:22575658). Isoform 1, but not isoform 2, is constitutively active, as evidenced by elevated basal cAMP levels, and responds to mechanical activation (shaking) (PubMed:26499266).[UniProtKB/Swiss-Prot Function]

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