Mouse Alg8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alg8
Locus ID	381903
Kit Components	GA217191G1, Alg8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217191G2, Alg8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217191G3, Alg8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_199035
Synonyms	AI447372; Gm1089
Summary	Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol before it is transferred to the nascent peptide (By similarity). Required for PKD1/Polycystin-1 maturation and localization to the plasma membrane of the primary cilia (PubMed:28375157).[UniProtKB/Swiss-Prot Function]

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