Mouse Drc1 activation kit by CRISPRa

CAT#: GA217162

Drc1 CRISPRa kit - CRISPR gene activation of mouse dynein regulatory complex subunit 1



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Drc1
Locus ID 381738
Kit Components

GA217162G1, Drc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA217162G2, Drc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA217162G3, Drc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001033460
Synonyms b2b1654Clo; Ccdc164; Gm1060
Summary Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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