Mouse Marchf4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Marchf4
Locus ID	381270
Kit Components	GA217090G1, Marchf4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217090G2, Marchf4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217090G3, Marchf4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001045533
Synonyms	BC056494; mKIAA1399
Summary	E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.[UniProtKB/Swiss-Prot Function]

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