Mouse Col27a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Col27a1
Locus ID	373864
Kit Components	GA216993G1, Col27a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216993G2, Col27a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216993G3, Col27a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025685
Synonyms	5730512J02Rik; AI449266
Summary	This gene encodes the alpha-1 subunit of type XXVII collagen, one of the low abundance fibril-forming collagens found in cartilage. The encoded protein forms a homotrimeric triple helical procollagen that undergoes proteolytic processing during fibril formation. Transgenic mice lacking a portion of the collagenous domain in the encoded protein exhibit skeletal abnormalities, chondrodysplasia and die at birth because of a lung defect. [provided by RefSeq, Dec 2015]

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