Mouse Tfap2e activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tfap2e
Locus ID	332937
Kit Components	GA216905G1, Tfap2e gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216905G2, Tfap2e gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216905G3, Tfap2e gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_198960
Synonyms	AI505200; AP-2e; Tcfap2e
Summary	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation.[UniProtKB/Swiss-Prot Function]

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