Mouse Tmem67 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem67
Locus ID	329795
Kit Components	GA216771G1, Tmem67 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216771G2, Tmem67 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216771G3, Tmem67 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177861, NR_110955
Synonyms	5330408M12Rik; b2b1163.1Clo; b2b1291.1Clo; B230117O07
Summary	Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (sftpc).[UniProtKB/Swiss-Prot Function]

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