Mouse Unc80 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Unc80
Locus ID	329178
Kit Components	GA216723G1, Unc80 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216723G2, Unc80 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216723G3, Unc80 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175510, NM_001368824, NM_001368825
Synonyms	C030018G13Rik; C230061B10Rik; UNC-80
Summary	Component of the NALCN sodium channel complex, required for channel regulation. This complex is a cation channel activated by neuropeptides substance P, neurotensin, and extracellular calcium that regulates neuronal excitability by controlling the sizes of NALCN-dependent sodium-leak current. UNC80 is essential for NALCN sensitivity to extracellular calcium.[UniProtKB/Swiss-Prot Function]

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