Mouse Sycp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sycp2
Locus ID	320558
Kit Components	GA216517G1, Sycp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216517G2, Sycp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216517G3, Sycp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177191
Synonyms	3830402K23Rik; 4930518F03Rik
Summary	Major component of the axial/lateral elements of synaptonemal complexes (SCS) during meiotic prophase. Plays a role in the assembly of synaptonemal complexes (PubMed:16717126). Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility (PubMed:16717126). Required for insertion of SYCP3 into synaptonemal complexes (PubMed:16717126). May be involved in the organization of chromatin by temporarily binding to DNA scaffold attachment regions. Requires SYCP3, but not SYCP1, in order to be incorporated into the axial/lateral elements.[UniProtKB/Swiss-Prot Function]

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