Mouse Adgrl3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adgrl3
Locus ID	319387
Kit Components	GA216273G1, Adgrl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216273G2, Adgrl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216273G3, Adgrl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347367, NM_001347368, NM_001347369, NM_001347371, NM_198702, NM_001359826, NM_001359828, NM_001359829, NM_001359830, NM_001359831, NM_001359832, NM_001359833, NM_001359834
Synonyms	5430402I23Rik; CIRL-3; D130075K09Rik; Gm1379; LEC3; Lphn3; mKIAA0768
Summary	Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells (PubMed:22405201, PubMed:25728924, PubMed:26235031). Plays a role in the development of glutamatergic synapses in the cortex (PubMed:22405201, PubMed:24739570). Important in determining the connectivity rates between the principal neurons in the cortex (PubMed:24739570).[UniProtKB/Swiss-Prot Function]

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