Mouse Washc4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Washc4
Locus ID	319277
Kit Components	GA216263G1, Washc4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216263G2, Washc4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216263G3, Washc4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033375
Synonyms	A230046K03Rik; AA589518; Kiaa1033; mKIAA1033
Summary	Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875).[UniProtKB/Swiss-Prot Function]

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