Mouse Prex1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Prex1
Locus ID	277360
Kit Components	GA216153G1, Prex1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216153G2, Prex1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216153G3, Prex1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177782
Synonyms	G630042G04; P-REX1; Setd6
Summary	Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils (By similarity).[UniProtKB/Swiss-Prot Function]

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