Mouse Adcy10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adcy10
Locus ID	271639
Kit Components	GA216111G1, Adcy10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216111G2, Adcy10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216111G3, Adcy10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_173029, NM_001357427
Synonyms	4930431D04Rik; 4931412F17; sAC; Sacy
Summary	Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels (By similarity). Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (PubMed:14976244, PubMed:16054031). Involved in ciliary beat regulation (By similarity).[UniProtKB/Swiss-Prot Function]

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