Mouse Irf2bp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irf2bp2
Locus ID	270110
Kit Components	GA216078G1, Irf2bp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216078G2, Irf2bp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216078G3, Irf2bp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164598
Synonyms	E130305N23Rik; IRF-2BP2
Summary	Acts as a transcriptional corepressor in a IRF2-dependent manner, this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation (By similarity).[UniProtKB/Swiss-Prot Function]

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