Mouse Rccd1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rccd1
Locus ID	269955
Kit Components	GA216061G1, Rccd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216061G2, Rccd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216061G3, Rccd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_173445
Synonyms	5830436H09; E430018M08Rik
Summary	Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8.[UniProtKB/Swiss-Prot Function]

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