Mouse Plch2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Plch2
Locus ID	269615
Kit Components	GA216026G1, Plch2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216026G2, Plch2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216026G3, Plch2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001113360, NM_175556, NM_001356470
Synonyms	A930027K05Rik; Plc-eta2; PLCeta2; Plcl4
Summary	The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain.[UniProtKB/Swiss-Prot Function]

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