Mouse Fbxo10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fbxo10
Locus ID	269529
Kit Components	GA216015G1, Fbxo10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216015G2, Fbxo10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216015G3, Fbxo10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001024142
Synonyms	FBX10; Gm634
Summary	Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2.[UniProtKB/Swiss-Prot Function]

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