Mouse Nrip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nrip1
Locus ID	268903
Kit Components	GA215964G1, Nrip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215964G2, Nrip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215964G3, Nrip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_173440, NM_001358238
Synonyms	6030458L20Rik; 8430438I05Rik; 9630050P12; AA959574; AW456757; RIP140
Summary	Modulates transcriptional repression by nuclear hormone receptors such as NR2C1, thyroid hormone receptor and retinoic acid receptor/RARA. Essential for cumulus expansion and follicle rupture during ovulation. Also controls the balance between fat accumulation and energy expenditure. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC.[UniProtKB/Swiss-Prot Function]

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