Mouse Mtmr12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mtmr12
Locus ID	268783
Kit Components	GA215955G1, Mtmr12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215955G2, Mtmr12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215955G3, Mtmr12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172958, NM_001356498
Synonyms	3Pap; 4932703C11; C730015A02Rik; mKIAA1682; Pip3ap
Summary	Acts as an adapter for the myotubularin-related phosphatases (PubMed:23818870). Regulates phosphatase MTM1 protein stability and possibly its intracellular location (PubMed:23818870). By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (PubMed:23818870).[UniProtKB/Swiss-Prot Function]

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