Mouse Agxt2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Agxt2
Locus ID	268782
Kit Components	GA215954G1, Agxt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215954G2, Agxt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215954G3, Agxt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001031851, NM_001310735, NM_001310736
Synonyms	AI303810; AI663818
Summary	Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.[UniProtKB/Swiss-Prot Function]

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