Mouse Zbtb1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zbtb1
Locus ID	268564
Kit Components	GA215936G1, Zbtb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215936G2, Zbtb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215936G3, Zbtb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178744, NM_001364323
Synonyms	9430077A12; AI256369; Bsg2; C430003J21Rik
Summary	Acts as a transcriptional repressor (By similarity). Represses cAMP-responsive element (CRE)-mediated transcriptional activation (By similarity). In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis (By similarity). Plays a key role in the transcriptional regulation of T lymphocyte development (PubMed:22201126, PubMed:22753936).[UniProtKB/Swiss-Prot Function]

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