Mouse Sh3pxd2b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sh3pxd2b
Locus ID	268396
Kit Components	GA215918G1, Sh3pxd2b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215918G2, Sh3pxd2b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215918G3, Sh3pxd2b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177364
Synonyms	fad49; G431001E03Rik; TSK4
Summary	Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.[UniProtKB/Swiss-Prot Function]

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