Mouse Tnfaip8l3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfaip8l3
Locus ID	244882
Kit Components	GA215232G1, Tnfaip8l3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215232G2, Tnfaip8l3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215232G3, Tnfaip8l3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033535
Synonyms	9930029P06Rik; Gm517
Summary	Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.[UniProtKB/Swiss-Prot Function]

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