Mouse Gp6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gp6
Locus ID	243816
Kit Components	GA215149G1, Gp6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215149G2, Gp6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215149G3, Gp6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163014
Synonyms	9830166G18Rik; Gm469; Gpvi
Summary	Collagen receptor involved in collagen-induced platelet adhesion and activation (PubMed:16139873, PubMed:24368846). Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.[UniProtKB/Swiss-Prot Function]

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