Mouse Zfp462 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zfp462
Locus ID	242466
Kit Components	GA215048G1, Zfp462 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215048G2, Zfp462 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215048G3, Zfp462 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172867
Synonyms	6030417H05; 9430078C22Rik; Gt4-2; Zfpip
Summary	Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization (PubMed:20219459, PubMed:21570965). Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG (PubMed:21570965). By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA (PubMed:17353115). Regulates neuronal development and neural cell differentiation (PubMed:21570965, PubMed:27621227).[UniProtKB/Swiss-Prot Function]

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