Mouse Dnai3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dnai3
Locus ID	242253
Kit Components	GA215035G1, Dnai3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215035G2, Dnai3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215035G3, Dnai3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172864
Synonyms	4931433A13Rik
Summary	Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization (By similarity). Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (PubMed:30060180). May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (PubMed:25498833).[UniProtKB/Swiss-Prot Function]

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