Mouse Tspyl5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tspyl5
Locus ID	239364
Kit Components	GA214846G1, Tspyl5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214846G2, Tspyl5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214846G3, Tspyl5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001085421
Synonyms	6330530B20; E130308C19Rik
Summary	Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. Involved in regulation of p53/TP53. Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2. Proposed to displace p53/TP53 from interaction with USP7 (By similarity).[UniProtKB/Swiss-Prot Function]

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