Mouse Sdk2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sdk2
Locus ID	237979
Kit Components	GA214767G1, Sdk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214767G2, Sdk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214767G3, Sdk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172800
Synonyms	4632412F08Rik; 5330435L01Rik; mKIAA1514; Sdk-2
Summary	Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion (PubMed:26287463). Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs and the excitatory amacrine cells VG3-ACs. Formation of synapses between these two cells plays a key role in detection of motion (PubMed:26287463). Promotes synaptic connectivity via homophilic interactions (PubMed:26287463).[UniProtKB/Swiss-Prot Function]

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