Mouse Ttll6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttll6
Locus ID	237930
Kit Components	GA214763G1, Ttll6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214763G2, Ttll6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214763G3, Ttll6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172799
Synonyms	4932418K24Rik; D11Moh43e; D11Moh44e; t8130b59
Summary	Polyglutamylase which preferentially modifies alpha-tubulin (PubMed:17499049, PubMed:21074048). Mediates tubulin polyglutamylation in cilia (PubMed:22246503). Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (PubMed:17499049, PubMed:21074048). Generates long side-chains (PubMed:20530212). Generates polyglutamylation of CGAS, leading to impair the DNA-binding activity of CGAS (PubMed:26829768).[UniProtKB/Swiss-Prot Function]

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